Avoid Downplaying Side Effects

Should we avoid protease inhibitors in first lines due to their lipid side effects? - cons

Treatment is medical risk management. In treatment decisions, the relative risks of interventions have to be weighed against each other, with long-term irreversible untoward events being most important to avoid. Resistance development is such a deleterious long-term effect, especially with lower adherence, as it reduces the numbers of options for successful long-term viral suppression. It is le...

Willingness to pay to avoid metastatic breast cancer treatment side effects: results from a conjoint analysis

PURPOSE Metastatic breast cancer (MBC) patients are treated with a variety of regimens with differing side effects that can reduce the patients' quality of life. This study assessed the willingness to pay (WTP) to avoid side effects related to MBC treatment using conjoint analysis. METHODS An online, self-administered conjoint analysis survey of US adult female MBC patients was conducted to e...

Downplaying Model Power in IT Project Work

(this article cites 6 articles hosted on the Citations commercial use or unauthorized distribution. Executives and information technology (IT) specialists often manage IT projects in project teams. Integrative IT systems provide opportunities to manage and restructure work functions, but the process of change often causes serious problems in implementation and diffusion. A central issue in the ...

Side Effects

Side Effects

This section covers basic topics and illustrates the technical notion of a computational effect with several mathematical and programming examples. In everyday language, a “side effect” refers to the unintended or unforeseen consequences of an action. By analogy, in order to identify the side effect of a given computation, it is first necessary to isolate the “publicly stated” or “publicly expe...